That is necessary, since the way a protein in the body folds determines if a pharmaceutical will have the ability to bind to that protein and work. In other words, we need to understand how these proteins fold if we desire a drug to work. Historically, this has actually been an experimental procedure (last week). Now, Alpha, Fold can anticipate protein folding with 92. 4% accuracy. That's going to make it a lot easier to develop drugs that do what they're designed to do. This was an advancement almost no one observed. However it's going to have profound implications for treating disease. I forecast that Alpha, Fold will be 98% accurate by the end of 2021.
And, obviously, there will be a lot of investment opportunities in this area, too. Moving topics It's going to be a great year for bitcoin. I'm bullish on it in 2021 (jeff brown top biotech 2020). That said, I still believe bitcoin will continue to be unpredictable. We're close to all-time highs. I would not be surprised if it pulled back perhaps significantly before going higher - bleeding edge. I have actually been covering bitcoin for a long time now. Among the very first research study reports I ever published was on bitcoin. That remained in June 2015. At the time, bitcoin was trading for about $240. Bitcoin trades for over $34,000 today.
However at the time of that initial suggestion, I titled my report "What's the Big Deal With Bitcoin?" That shows you where the conversation was at the time. We were primarily informing readers. But that's not the huge question any longer. Now we're seeing institutional cash lastly take an interest in bitcoin. Massachusetts Mutual Life Insurance coverage took a $100 million stake in bitcoin in December. This is not some little, niche enterprise. Mass, Mutual is a trusted 170-year-old organization. So believe about that. In 5 years, we went from informing readers on what bitcoin is to a business like Mass, Mutual taking a $100 million stake.
Which's a big factor I'm bullish on it this year. korean actress. Regards, Jeff Brown, Editor, The Bleeding Edge I have a bonus forecast 2020 was a record year for IPOs. 552 U.S. companies went public the most in more than twenty years. These companies raised a total of $172 billion. That's an all-time high beating the previous yearly record by 43%. I predict 2021 will be another record year in IPOs. There are many fantastic private business on the brink of striking the public markets And I have actually been dealing with a brand-new method for you to invest even before these companies go public.
This opportunity has been constructing over the last couple of years. I can't wait to inform you all about it. Join me tomorrow at 8 p. m. ET for my Pre-IPO Code Occasion to find out all the details. Go right here to book your area free of charge.
Emma Walsh here, handling editor of the Journal. Regular Journal readers know that tech isn't our usual beat (jeff brown biotech genome sequencing). And when it pertains to tech investing, we leave it to the experts. Thankfully, we have several such professionals in our Rolodex. Our colleague Jeff Brown will recognize to our long time readers. He is one of the most accomplished tech investing professionals we understand (biotech stocks). In fact, he had a number of triple-digit returns in his Brownstone Research portfolios last year. Here's what Jeff thinks the tech sector will bring us in 2021 Each year, I like to have a look at the huge photo and forecast what's simply around the corner.
That consists of things like 5G networks, biotech, expert system, and far more. These trends are experiencing exponential development and producing unbelievable opportunities for investors. I desire to ensure all our readers are prepared for what's next. And with that in mind, let me draw the photo of what I see being available in the next 12 months Our new 5G (fifth-generation) cordless networks are a subject I have actually been covering for years now. legacy report prediction. But in spite of what many readers may think, this is a pattern that's simply beginning. Even though the COVID-19 pandemic interrupted supply chains last year, an outstanding 250 million 5G-enabled devices were still offered.
And all of this ultimately led to Apple delaying the release of the 5G-enabled i, Phone 12 by 2 months (last week). Losing 2 months of manufacturing and sales really affects how numerous 5G gadgets are sold in the calendar year. When you think about all of that, selling 250 million units is impressive. More significantly, the delays triggered by the pandemic produced a lots of suppressed demand. And that need is now going to be pushed into 2021. In reality, I forecast that more than 500 million 5G devices will be shipped in 2021 - legacy report prediction. Which's not my only 5G forecast When I have actually discussed 5G in the past, I have actually described its three various phases.
In Phase 2, 5G gadgets go on sale. 5G phones and other products begin to reach consumers. And in Phase 3, 5G services begin to be offered (last week). That's when we start to see applications running on 5G networks. Think about things like massive multiplayer games over a mobile phone. That's not possible with 4G. It will be with 5G. And my 2nd 5G forecast for 2021 is that we will start Stage Three by this summer season. This starts something of a virtuous cycle: The majority of people do not truly appreciate the technology. But they will care if there are amazing applications that can just be accessed with a 5G phone.
That leads to more 5G apps being developed. In reality, 5G is going to open a suite of unbelievable applications: self-driving automobiles, the Internet of Things, robotic surgical treatment, and more. All of these innovations need 5G. The financial investment opportunities moving forward will be massive. Stepping far from 5G, the next important technology I visualize in 2021 is CRISPR genetic modifying. CRISPR means "clustered routinely interspaced brief palindromic repeat." It's a mouthful. But it's one of the most interesting advancements in biotechnology. At a high level, CRISPR is an innovation that can edit our genetic makeup as if it were software.
The program can crash or not operate properly. CRISPR uses a similar concept however with our genetic code. "Typos" in our genome can result in illness. CRISPR can correct these "typos." For several years, CRISPR was mainly a niche innovation that wasn't well understood. And throughout that time, there were actually just three business operating in this area. However things are changing. CRISPR is no longer just theoretical. We're seeing actual outcomes. We're treating diseases and seeing that this technology simply works. And as an outcome, a "second crop" of early-stage CRISPR companies is going public and delivering incredible returns. This entire market is efficiently a greenfield opportunity.
There's space for many business to exist in this area. angel investor. And there will be more. That's my prediction for CRISPR in 2021. I forecast that two or three more genetic modifying companies will hold their IPOs. Sticking to biotechnology, we are seeing fantastic things taking place at the merging of biotech and synthetic intelligence (AI). Google's AI subsidiary, Deep, Mind, simply announced at the end of 2020 that its latest Alpha, Fold software can properly forecast the folding of a protein based solely on its amino acid series with 92. 4% precision. That is very important because the method a protein in the body folds figures out if a pharmaceutical will be able to bind to that protein and work.
Historically, this has been an experimental procedure. However now, Alpha, Fold can forecast protein folding with 92. 4% accuracy. That's going to make it much easier to create drugs that do what they're developed to do. And here's my next prediction. I predict that Alpha, Fold will be 98% accurate by the end of 2021. And we will see not just one however several drug therapies produced utilizing this technology. This was one of those developments that nearly no one noticed. But it's going to have extensive implications for treating illness. And, naturally, there will be lots of financial investment opportunities in this space, too.
It's going to be a good year for bitcoin. I'm bullish on it in 2021. That stated, I still think bitcoin will continue to be volatile. We're close to all-time highs. I wouldn't be amazed if it pulled back maybe significantly before going greater. I've been covering bitcoin for a long time now. One of the very first research study reports I ever released was on bitcoin - jeff brown investor prediction. That remained in June 2015. At the time, bitcoin was trading for about $240. Bitcoin trades for over $40,000 today. So that's a 16,500%+ return on investment for anybody who followed my recommendation. However at the time of that preliminary suggestion, I entitled my report, "What's the Big Deal With Bitcoin?" That reveals you where the discussion was at the time.
However no one is asking that question anymore. Now, we're seeing institutional money finally taking an interest in bitcoin. The huge news was that Massachusetts Mutual Life Insurance coverage took a $100 million stake in bitcoin in December. This is not some little, niche business. jeff brown top stock pick 2021. Mass, Mutual is a 150-year-old institution. So think about that. In 5 years, we went from educating readers on what bitcoin is to a company like Mass, Mutual taking a $100 million stake. The institutional adoption of bitcoin will continue. And that's a huge reason I'm bullish on it this year. Regards, Jeff Brown, Editor, The Bleeding Edge I have another perk prediction In 2021, we're going to have another record year in IPOs. One site reports that Jeff Brown deserves about $27. 5 million and claims the information depends on date as of February 2021, but we might not independently validate this claim. Given Jeff Brown's past, he likely has a significant net worth, however we can't hammer down an accurate figure at this minute. Brown is best known for his sage-like capability to choose winning technology stocks. He spent more than 25 years looking into technology companies like Qualcomm, NXP semiconductors, and Juniper Networks. Brown's extensive experience offers him an exceptional perspective on the market. He's constantly on the hunt for new opportunities, and he shares a number of his best picks in the Near Future Report.
That's high praise, but it's not ridiculously reasoned. Brown has an exceptional track record as a stock-picker, and he effectively anticipated a few of the most significant financial events of the past 20 years. Although he does not appear to release his choices to the general public, the service's success is a direct sign of Brown's stock-picking prowess. No one on Wall Street gets it right whenever, but Jeff Brown's accurate forecasts have made him legions of devoted fans. That states a lot about his ability. The Future Report is published by Brownstone Research study, a prominent monetary research publisher. Brownstone Research study provides a number of research study services with a wide array of expertises - jeff brown predictions 2021.
The company is likewise affiliated with Bonner & Partners, another well-respected research study publisher - second wave. On its website, Brownstone says its objective is to offer retail financiers with professional-grade research: "For too long, the very best investment research has actually not been readily available to individual financiers. It has been generally scheduled for financial investment banks, hedge funds, personal equity, and high-net-worth clients. what is the legacy report predicting. The objective of Brownstone Research study is to make that sort of exclusive research study readily available to any investors seeking to gain an edge in the marketplaces. The objective is simple to deliver special and profitable financial investment research discovered nowhere else." -Brownstone Research study site excerpt from the Jeff Brown is the creator of Brownstone Research, and he also works as the company's Chief Investment Expert.
With Brown guiding the ship, Brownstone Research study is a powerhouse publisher with lots to use its clients. After decades of stable success at the helm of top-tier business like Tesla and Area, X, Elon Musk is a household name throughout most of America. If you know even a little bit about the marketplace, you understand that he has a credibility as a King Midas of sorts. the legacy report predictions. Whatever he touches relies on gold! Jeff is aware of Elon Musk's executive expertise, so he always has an eye out for the Silicon Valley rock star's next relocation. This time, Jeff has an early lead on Elon's next big job.
In truth, Brown thinks S.A.V. white house. could be "the greatest trend of the 2020s, and he's not alone. Have a look at these quotes from other popular S.A.V. bulls: Elon's next huge act will be marrying 2 cutting-edge innovations: expert system and electrical vehicles. Musk hopes the combination will help him establish the very first fully-autonomous, self-driving cars ever. It's absolutely nothing short of the automotive market's Holy Grail. As you know, electrical vehicles and self-driving car stocks have been substantial this year, but the Wall Street device has actually approved hype without much tangible result. Despite an extreme boost in competitors over the past couple of years, Brown still believes Musk has the best possibility of putting everything together.
tech might be the magic string that connects it all together. S.A.V. means Shared Autonomous Lorry, and it could be the future of transport. Generally, this innovation would allow you to rent your car as an autonomous, self-driving taxi when you're not utilizing it. You simply leave the cars and truck and press a button on an app that informs the car to "sign up with the fleet." Next thing you understand, you're relaxing on your couch while your automobile shuttles ride-sharers around town. Most importantly, you get to keep a significant piece of the revenues. It sounds outrageous, however it might be closed than you believe.